Nerve Fresh was designed to eliminate the root causes of neuropathy, whether peripheral, proximal, cranial, autonomic, or focal. Neuropathy is nerve damage that results from different health conditions (e.g., diabetes, chemotherapy, HIV, shingles, alcoholism, nutrient deficiencies, etc.).

Although these conditions are usually irreversible, measures can be implemented to help prevent neuropathy or at least better manage associated symptoms. According to the Premier Vitality team, research suggests three enzymes that, when overactive, “strip down the collagen [or skin protein] of glue that binds skin cells together.” Consequently, sensory nerve endings degenerate, interfering with much of our sensory information, such as temperature, pain, and mechanical stimulation of the central nervous system. These culprits are said to be responsible for many of the symptoms associated with nerve damage, including but not limited to numbness, muscle fatigue, hot-like sensations in the skin barrier, pulsation, and nerve degeneration.

What are these culprits, you ask? They are none other than COX-2, PGE-2, and MMP-13. From its looks, the trio shares inflammatory effects. As reported by one team of Nature researchers, cyclooxygenase-2 (COX-2) is an enzyme best known for triggering pro-inflammatory processes that are known to aggravate neuronal degeneration. Similarly, PGE-2 is an enzyme that has been demonstrated to promote neuronal inflammation and degeneration in many neurological diseases, such as ischemic stroke, epilepsy, neurodegenerative diseases, brain tumors, and inflammation, among others.

Finally, there’s MMP-13 , which is precisely what induces the degradation of the collagen between skin cells, causing nerve damage. Inflammation in small or manageable quantities is good, as this process triggers immune responses to an injury or infection. Things become a problem when the body is in a chronic state of inflammation, which induces a consistent fight-or-flight response for no reason. In succession, individuals are at risk of heart disease, arthritis, depression, Alzheimer’s, and others.

It is important to note that a supplement like Nerve Fresh only tends to do some healing; the rest comes from lifestyle choices. This means avoiding unhealthy food and beverages and focusing on getting enough exercise, sleep, and stress management.

With this introductory knowledge, we can now navigate the ingredients that make Nerve Fresh a potential candidate for easing nerve damage symptoms.